Myasthenia Gravis Association of B.C.

Cautions

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The following is a list of medications that should be take with caution.  Drugs that are underlined are considered dangerous in Myasthenia Gravis.

CONSULT WITH YOUR PHYSICIAN BEFORE CHANGING OR STOPPING ANY MEDICATIONS

ANALGESICS
Narcotics including: Codeine, Hydromorphone (Dilaudid), Meperidine/Pethedine (Demerol), Morphone and Opium Alkaloids (Pantopon).

ANESTHETICS, GENERAL
Methoxyflurane, Thiopental Sodium (Pentothal)

ANESTHETICS, LOCAL
Procaine (Novocaine)

ANTI-CHOLINERGICS
Oxybutunin (Ditropan), Procyclidine (Kemadrin), Propantheline Bromide (Probanthine), Trihexyphenidyl (Artane).

ANTICONVULSANTS
Barbituates, Diazepan (Valium), Ethosuxamide, Lorazepam (Ativan), Magnesium, Paraldehyde, Phenytoin, (Dilantin), Trimethadione.

ANTIHISTAMINES
Diphenydramine (Benadryl), Hydroxyzine (Atarax).

ANTI-INFECTIVES
Aminoglycosides; including Amikacin, Gentamycin, Kanamycin, Neomycin, Netilmicin Sulfate, Paromomycin, Streptomycin, Tobramycin.
Ampicillin, Azithromycin (Zithromax) Bacitracin, Ciprofloxacin, Clindamycin, Colistin Sulfate, Colistimethate (Coly-mycin M) Erythromycin, Imipenem (Primaxin), Lincomycin, Metronidazole (Flagyl) Polymyxin A, Polymyxin B, Pyrantel Pamoate, Sulfonamides, Tetracyclines including Doxycycline (Vibramycin) Vancomycin, Viomycin.

ANTI-MALARIALS
Chloroquine, Quinine.

ANTI-RHEUMATICS/ GOUT THERAPY
Cloroquine, Colchicine, D-penicillamine (Cuprimine)

CARDIOVASCULAR DRUGS
ACE (angiotensin-converting enzyme) Inhibitors, including Quinapril (Accupril)
Beta-Blockers including acebutolol, Atenolol (Tenormin), Labetalo (Trandate), Nadolol (Corgard), Oxprenolol (Trasicor), Pindolol, Practolol, Propanolol (Inderal), Sotalol (Sotacor), Timolol (Blocadren).
Bretylium,
Calcium Channel Blockers, including Verapamil (Isoptin)
Lidocaine, Phenytoin (Dilantin), Propafenone (Rythmol), Quinidine sulfate, Trimethaphan.

CNS DEPRESSANTS

COMMON COLD PREPARATIONS
including Emetine (in Cophylac Expectorant)

CONTRAST AGENTS
Iothalamic acid, Diatrizoate meglumine.

CORTICOSTERIODS
Probably all steriods, including Methylprednisone, Prednisolone, Prednisone.

DIURETICS
including Acetazolamide (Zaroxylin)

HORMONES
ACTH

IV FLUIDS
Sodium Lactate solution

MAGNESIUM
Magnesium, or preparations containing Magnesium.

MUSCLE RELAXANTS
Any muscle relaxant in suspect, including Carisprodol (Soma), Chlorzoxazone (Paraflex, Parafon forte), Cyclobenzaprine (Flexeril), Diazepam (Valium), Meprobamate, methocarbamol (Robaxin), Orphenadrine Citrate (Norflex)

NEUROMUSCULAR BLOCKING AGENTS
Botulinum Toxin type A (Botox), Curare derivatives including Metocurine (Diemethyltubocurarine) Tubocurarine, Decamethonium bromide (Syncurine), Gallamine (Flaxedil), Pancuronium, Succinylcholine (Anectine) THIS CLASS OF DRUGS IS USED FOR PARALYSING MUSCLES. VENTILATION SUPPORT MUST BE AVAILABLE!

OCULAR (EYE) DRUGS
Echothiophate (Phospholine iodide), Mydriatics, Proparacaine (Alcaine, Opthetic), Timolol, Tropicamide (Mydriacyl)

PSYCHOTROPICS
Amitriptyline (Elavil),Amphetamines, Chlorpromazine (largactil), Droperidol (Inapsine), Haloperidol (haldol), Imipramine (Tofranil), Lithium Carbonate, Paraldehyde, Promazine.

RESPIRATORY DEPRESSANTS

SEDATIVES / HYPNOTICS
Barbituates
Banzodiazepines, including; Chlordiazepoxide (Librium), Clorazepate (Tranxene), Diazepam (Valium), Flurazepam (Dalmane), Halazepam (Paxipam), Lorazepam (Ativan), Oxazepam (Serax), Temazepam (restorial), Triazolam (Halcion).
ChloralHydrate.

TRANQUILIZERS

OTHERS
Amantadine (Symmetrel) for treating influenza and Parkinsons.
Carnitine, Chlorine gas, DDT, Interferon Alpha, Levonorgestrel implant (Norplant) for contraception. Nicotine Transdermal Patch.

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